黑色的秀髮，最主要是由真黑素(Eumelanin)天然染成。662Please respect copyright.ＰＥＮＡＮＡWGdy538Yq8
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（圖2）皮膚下的黑素細胞(Melanocyte)會製造出黑色粒子Melanosomes，而這些黑色粒子Melanosomes會走到表皮(Epidermis)或者髮囊(Hair follicile)，賦予皮膚及頭髮黑色外表。662Please respect copyright.ＰＥＮＡＮＡkYFwFhzUtf
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（圖3）圖中為Melanosomes裡頭的生物化學反應，起始材料為氨基酸，經過一輪酶素的化學反應後，最終成品將為黑色真黑素及啡色真黑素。662Please respect copyright.ＰＥＮＡＮＡd3XX64d34d
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而根據兩者比例的不同，最終的顏色效果亦會有所不同，所以Melanosomes並不一定是純黑色，亦因而解釋了為何並不是所有人的頭髮也是漆黑黑一片。662Please respect copyright.ＰＥＮＡＮＡObyiMe2cqo
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值得留意的是，這一系列發生在Melanosomes的反應均是在中性pH7的環境下進行，有別於現時常用的鹼性pH化學染髮方式。662Please respect copyright.ＰＥＮＡＮＡs6qsHP6GaJ
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有科學家看準這一點，因而嘗試照辦煮碗在體外套用我們自身Melanosomes蛋白酶的機制方式進行染髮（Ref1)。662Please respect copyright.ＰＥＮＡＮＡKSdJ2lwWZ6
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（圖4）從圖中可見，鹼性pH化學染髮以及中性pH7模仿人類Melanosomes裡頭生物化學反應方式染髮（2小時，攝氏35度），兩者最終的外表差別不大。662Please respect copyright.ＰＥＮＡＮＡMLqlthGo4w
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而且經過5次清水沖洗及10分鐘的洗髮水猛烈沖洗後，兩者亦沒有出現脫色的現象。662Please respect copyright.ＰＥＮＡＮＡYC5bBjQ4Uk
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只不過，利用鹼性pH化學染髮的話，色素會徹底進入髮質內部。662Please respect copyright.ＰＥＮＡＮＡPBvv8jYMho
反觀中性pH7生物化學反應方式染髮，色素主要聚集在髮質外部，因此對頭髮的傷害相對較低。662Please respect copyright.ＰＥＮＡＮＡpaTClcnIXE
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（圖5）在圖中亦可以清楚看得到，鹼性pH化學染髮對頭髮外部會做成傷害(箭嘴所指位置)，662Please respect copyright.ＰＥＮＡＮＡUxs2O99cKP
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而中性pH7模仿人類Melanosomes裡頭生物化學反應方式染髮則沒有這個問題。662Please respect copyright.ＰＥＮＡＮＡatIgBGo0na
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此方法能否在日後淘汰鹼性pH化學染髮或其他的染髮手段，我們將可拭目以待。662Please respect copyright.ＰＥＮＡＮＡCvY3Qx6NuO
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如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。662Please respect copyright.ＰＥＮＡＮＡegtYpC5w5N
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc662Please respect copyright.ＰＥＮＡＮＡIyZ07zSyMM
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。662Please respect copyright.ＰＥＮＡＮＡZgdgX9udzB
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https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio662Please respect copyright.ＰＥＮＡＮＡ17cQqEGXoN
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有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。662Please respect copyright.ＰＥＮＡＮＡHEvVxFosSN
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Ref1:https://pubs.acs.org/doi/pdf/10.1021/acs.chemmater.0c02790
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